"We are profoundly saddened by the tragic passing of Jaylon Ferguson," the team said in a statement. "He was a kind, respectful young man with a big smile and infectious personality.
We express our heartfelt condolences to Jaylon's family and friends as we mourn a life lost much too soon."
At approximately 11:25 p.m. Tuesday, Baltimore Police said officers responded to a home in the northern district of the city, where they found Ferguson unresponsive and being treated by medics.
Ferguson never regained consciousness and was pronounced dead on the scene by medics, according to police.
Baltimore Police said there were no signs of trauma found or foul play suspected at this time.
Ferguson's body was transported to the medical examiner's office, where a cause of death will be determined. Investigators are not ruling out the possibility of an overdose, a police spokesperson said
Ferguson, a third-round pick by the Ravens in 2019, had participated in all of the team's offseason practices this year.
Known as "Sack Daddy" coming out of Louisiana Tech, Ferguson holds the FBS record for career sacks with 45. In three NFL seasons, he totaled 67 tackles and 4.5 sacks.
"The LA Tech Family mourns this morning's tragic news of the sudden death of former Bulldog great, Jaylon Ferguson," the Louisiana Tech football team tweeted.
Ferguson had three children, two daughters and a son, who are all under the age of 5.